Weight loss drugs

In recent months, A-list celebrities have openly shared that they have taken drugs like Ozempic and Wegovy to lose weight. This has prompted a huge demand for these sorts of medicines from the broader public and created supply chain shortages for drugs like Ozempic, significantly impacting the management of patients living with diabetes (for whom this drug is actually intended).

Facts
  • Supply Issues: This increased demand has created shortages of Ozempic, which is primarily intended for managing Type 2 diabetes, affecting patients who rely on it for blood sugar control.
  • How They Work: Ozempic and similar medications are classified as GLP-1 receptor agonists. They mimic the hormone GLP-1, targeting brain areas that regulate appetite, slowing stomach emptying, and enhancing insulin production while reducing liver sugar release.
  • Approved Medications: The GLP-1 class includes Semaglutide (Ozempic, Rybelsus), Liraglutide (Victoza), Dulaglutide (Trulicity), and Exenatide (Byetta), with most available in South Africa, except Rybelsus. For weight loss, higher doses of Liraglutide (Saxenda) and Semaglutide (Wegovy) are recognized but are not registered locally.
  • Side Effects: Common side effects include nausea, vomiting, diarrhea, headache, stomach pain, and fatigue, emphasizing the need for medical supervision when using these drugs.
  • Obesity complications: Obesity significantly increases the risk of various health conditions, including diabetes and heart disease. Healthy eating and exercise are foundational for weight management, but some may require medication as part of a comprehensive approach.
Actions
  • If considering these medications, consult a healthcare professional to assess suitability.
  • Understand that healthy eating and exercise are essential for effective weight management alongside medication.
  • Be aware that weight loss is not guaranteed without lifestyle changes; maintain a balanced approach for long-term success.
  • Research the costs and ensure you have coverage or savings for ongoing use, as these medications can be expensive.
  • Stay vigilant against counterfeit drugs due to high demand; only obtain prescriptions from licensed healthcare professionals.
  • Engage in comprehensive weight loss programs that include medical supervision for personalised treatment.
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